Accelerating innovation in the pharmaceutical industry

The key to success in the pharmaceutical industry is innovation.


The key to success in the pharmaceutical industry is innovation. Courtesy: CannonDesignDespite stronger cost pressures than in previous decades, organizations are expected to innovate, develop new products and bring them to market at an accelerated rate. Surprisingly, many of the industry's leaders are trying to navigate this complex and challenging industry with stale business models. Although science has consistently led the knowledge economy, its siloed nature, underfunding and linear processes have progressively reduced it to a transactional operation.

Not surprisingly, the R&D facilities at the center of these dated business models are also behind the times. Modern scientists may be pursuing cutting-edge solutions, but they're often doing so in uninspiring facilities and hierarchical organizations. They're often separated from one another in formally arranged spaces, reflecting linear process and static functionality. Such facilities and structures simply don't sync with the needs of "new science."

With over 50% of today's scientists born after 1980 and over 70% of existing labs more than 50 years old, the current and emerging R&D workforce seek new solutions. These highly collaborative, generationally diverse scientists are demanding radically new open source workplaces where the walls between disciplines are removed, the boundaries between discovery and commercialization are blurred and real-world problems are addressed in collaborative coexistence.

Pharmaceutical companies looking to create R&D facilities responsive to "new science" may find a leading example from the world of academic medicine. The Gates Vascular Institute and Clinical Translational Research Center (GVI/CTRC) in Buffalo, NY, is the result of a unique public/private partnership between Kaleida Health and the University of Buffalo (UB). The first-of-its-kind facility stacks a research building over a vascular institute and connects them via a BioSciences Incubator to drive innovation forward. Since opening, GVI/CTRC has driven more than $130 million of economic impact, created new jobs, launched biomedical start-ups and helped both organizations recruit Tier 1 Placements.

Here are four unique design strategies that define GVI/CTRC and position it at the forefront of "new science."

Integrated design plan

The key to success in the pharmaceutical industry is innovation. Courtesy: CannonDesignSuccessful modern R&D facilities can no longer be driven by lab design expertise alone. The GVI/CTRC required a remarkably synchronized design effort spanning leaders from science, higher education, healthcare, architecture, engineering, cost estimating, business consulting, interior design and construction management. This diverse team helped Kaleida Health and the University of Buffalo move beyond an original plan that called for two separate facilities and realize the value of combining their resources in one facility. Once this breakthrough was realized, the team then worked with leaders from both organizations to enhance every aspect of this dual-client's physical and enterprise success. At the core of GVI/CTRC's success was the realization that myriad perspectives would need to influence the design in order to achieve optimal outcomes.

Bench-to-bedside collaboration

Sandwiched between the GVI and the CTRC is a collaborative core containing education and conferences spaces, along with a 4,000 sf business incubator that allows doctors, researchers and entrepreneurs to meet in a variety of dynamic situations to accelerate medical discoveries. This creative design solution literally moves science from the bench to the bedside. Within GVI/CTRC, researchers can monitor real-time surgical procedures and then simply walk upstairs to begin testing ideas for new medical applications or products. Conversely, doctors are able to share challenges and needs with world-class researchers during opportunistic and informal meetings throughout the day.

This culture of collaboration is enhanced further by open-plan laboratories that allow for increased flexibility, innovation and collaboration. Open-plan laboratories eliminate the physical and figurative barriers between researchers and disciplines to promote the open exchange of ideas and cross-disciplinary collaboration required to best solve today's medical challenges.

Maximizing technology

Traditional laboratories are remarkably inefficient. Research over the past few years indicates scientists spend less than 40% of their time in the lab and that 50% of lab space is incorrectly used. Oftentimes, this inefficiency is exacerbated by technology and communications systems that aren't synchronized — leading to researchers wasting time while duplicating communication efforts or repeatedly walking from lab to office to record progress and updates. GVI/CTRC embraces modern technology and empowers its users to record information and communicate with each other at any time from any place within the facility. Seamless connectivity to technology systems that house data and analytics at strategically located work benches, touch down areas and collaboration zones inspired by best practices from corporate workplaces allow researchers to complete their work as they move from one effort to the next. This reduces time wasted, improves efficiency, and creates a continuous platform for real-time solutions.

Ready for the future

Everything moves rapidly in the pharmaceutical world. The challenges faced, the solutions needed, emerging sciences and technologies all change constantly. The GVI/CTRC will be able to endure and thrive amidst this change thanks to the universal grid design application- a standardized structural grid consisting of the optimum set of vertical and horizontal dimensions for a building's structure to allow for radical adaptability to medical, science and research functions. This grid makes GVI/CTRC almost infinitely adaptable and will significantly extend the building's valuable life by accommodating the wide range of potential sciences and technologies it will need to support. This prototype design strategy proved a key driver for the building's fast-track delivery, under budgeted cost and achieves a reduction in the engineering needs of HVAC, plumbing and electrical systems operational costs by $10 per sf. All of these features will help GVI/CTRC deliver valuable ideas for global health at lower expense for the next century.

The GVI/CTRC represents a breakthrough model for accelerating medical discovery that leading pharmaceutical companies should look to for guidance as they restructure their R&D departments and facilities. The future of the industry will be driven by those organizations that embrace new science and organize themselves to maximize its potential. GVI/CTRC is powerful look at where medical science is headed - and a guidepost for pharmaceutical organizations eager to lead the charge.

— Deb Sheehan, executive director of client strategies team, CannonDesign has overseen more than $4 billion in design solutions for healthcare systems worldwide. This article originally appeared on CannonDesign. CannonDesign is a CFE Media content partner.

No comments
Consulting-Specifying Engineer's Product of the Year (POY) contest is the premier award for new products in the HVAC, fire, electrical, and...
Consulting-Specifying Engineer magazine is dedicated to encouraging and recognizing the most talented young individuals...
The MEP Giants program lists the top mechanical, electrical, plumbing, and fire protection engineering firms in the United States.
Commissioning lighting control systems; 2016 Commissioning Giants; Design high-efficiency hot water systems for hospitals; Evaluating condensation and condensate
Solving HVAC challenges; Thermal comfort criteria; Liquid-immersion cooling; Specifying VRF systems; 2016 Product of the Year winners
MEP Giants; MEP Annual Report; Mergers and acquisitions; Passive, active fire protection; LED retrofits; HVAC energy efficiency
Driving motor efficiency; Preventing Arc Flash in mission critical facilities; Integrating alternative power and existing electrical systems
Putting COPS into context; Designing medium-voltage electrical systems; Planning and designing resilient, efficient data centers; The nine steps of designing generator fuel systems
Designing generator systems; Using online commissioning tools; Selective coordination best practices
As brand protection manager for Eaton’s Electrical Sector, Tom Grace oversees counterfeit awareness...
Amara Rozgus is chief editor and content manager of Consulting-Specifier Engineer magazine.
IEEE power industry experts bring their combined experience in the electrical power industry...
Michael Heinsdorf, P.E., LEED AP, CDT is an Engineering Specification Writer at ARCOM MasterSpec.
click me